Olga V. Zorkina, Cand. Sc. (Engineering), Docent, Head of the Department of Biology and Bioengineering, Volgograd State University, e-mail: ov.zorkina@volsu.ru
Alexander A. Maslennikov, Dr. Sc. (Biology), Senior Researcher, Head of the Laboratory of Environmental Toxicology, Scientific Research Institute of Hygiene, Toxicology and Occupational Pathology of the Federal Medical and Biological Agency; Associate Professor at the Department of Biology and Bioengineering, Institute of Natural Sciences of the Volgograd State University, e-mail: maslennikov@rihtop.ru
The role of the discipline “Preventive toxicology” in the educational program of undergraduate biology students is considered. Attention is paid to the necessity of deep understanding of toxic effects of chemical compounds on various bio-objects, including humans. Students should have an idea of the subject, goals and objectives of toxicology, toxicity and hazard of chemical compounds, toxicokinetics and toxicodynamics. The leading areas of study are acute, subacute and chronic toxicity of chemical substances at different ways of their entry into the body of contacting persons, the ability to cumulation, adaptation of the organism, combined, complex and combined effects, the basic principles of toxicometry. In addition to the above, it is necessary to master the important direction of “Preventive toxicology”, which studies the remote effects of chemical substances on the mammalian organism, manifested in the remote life of the biological object or its offspring (mutagenicity, carcinogenicity, gonadotoxicity, embryotoxicity, teratogenicity). The final section of the course involves consideration of the features of hygienic normalization of ecotoxicants in the production area and various environmental objects, with justification of the appropriate maximum permissible concentrations, extrapolation of data. The discipline contributes to the formation of an integrated approach to ecology, biomedical sciences and biotechnology. The advantages and relevance of this field of knowledge are considered, as well as the importance of preventive measures in handling chemicals.
Keywords: preventive toxicology, remote effects, ecology, education, master's degree, Biology, human health, ecosystems
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